What are Duodart tablets used for?

Duodart is indicated for the management of moderate to severe symptomatic benign prostatic hyperplasia (BPH).

What are the side effects of Duodart tablets?

You may also experience a decrease in sperm count and semen volume. One side effect of DUODART is known as “retrograde ejaculation”. When this happens most of the ejaculation fluid runs back into the bladder instead of being squirted out. Retrograde ejaculation is painless.

How long can you take Duodart?

How long to take it for. It is important to continue to take DUODART for as long as your doctor prescribes it, even if you do not feel any immediate benefit. Some men notice an early improvement in their symptoms however others may need to continue for 3-6 months to see if DUODART helps them.

How long does Duodart take to work?

Prostate volume starts to decrease from 1 month after starting dutasteride; maximum effect on symptoms and prostate size can take up to 6–12 months. Serum prostate specific antigen (PSA) levels are reduced by up to 50% after 6–12 months of dutasteride treatment, even if prostate cancer is present.

When is the best time to take Duodart?

Duodart must always be taken with a glass of water, up to 30 minutes after a meal. It must never be taken on an empty stomach. Ideally it should be taken at the same time of the day (this means with the same meal).

What time of day should you take Duodart?

The recommended dose of DUODART is one capsule (0.5 mg/ 0.4 mg) taken orally approximately 30 minutes after the same meal each day. Capsules should be swallowed whole and not chewed or opened.

What drugs should not be taken with Duodart?

DUODART should not be used in combination with other alpha-1 adrenergic blockers. Concomitant administration of tamsulosin hydrochloride and ketoconazole (a strong CYP3A4 inhibitor) resulted in an increase of the Cmax and AUC of tamsulosin hydrochloride by a factor of 2.2 and 2.8 respectively.

Is it possible to shrink an enlarged prostate?

5-alpha reductase inhibitors. These medications shrink your prostate by preventing hormonal changes that cause prostate growth. These medications — which include finasteride (Proscar) and dutasteride (Avodart) — might take up to six months to be effective.

What is Duodart ® (dutasteride) used for?

more… Duodart ® (dutasteride and tamsulosin hydrochloride) capsules are indicated for the treatment of symptomatic BPH in men with an enlarged prostate. Dutasteride-containing products, including Duodart, are not approved for the prevention of prostate cancer.

What are the active ingredients in Duodart?

dutasteride 500 micrograms dissolved in a liquid tamsulosin hydrochloride 400 micrograms. DUODART capsules also contain the inactive ingredients: glyceryl caprylate/caprate butylated hydroxytoluene

How should I take Duodart?

Swallow your DUODART capsules whole with some water, approximately 30 minutes after the same meal each day. It is very important that DUODART is not taken on an empty stomach as this may increase the risk of adverse effects. Don’t chew or open the capsules.

Are there any clinical trials conducted with Duodart?

There have been no clinical trials conducted with Duodart; however, coadministration information for years 1 and 2 is available from the CombAT (Combination of Avodart and Tamsulosin) study, a comparison of dutasteride 500 microgram and tamsulosin 400 microgram once daily for four years as co-administration or as monotherapy.