How often is DACOGEN given?

DACOGEN Regimen Options Administer DACOGEN at a dose of 15 mg/m² by continuous intravenous infusion over 3 hours repeated every 8 hours for 3 days. Repeat cycles every 6 weeks upon hematologic recovery (ANC at least 1,000/μL and platelets at least 50,000/μL) for a minimum of 4 cycles.

How often is decitabine administered?

2.1 Recommended Starting Dosage Administer DACOGEN at a dose of 15 mg/m2 by continuous intravenous infusion over 3 hours repeated every 8 hours for 3 days.

What is DACOGEN drug used for?

This medication is used to treat a group of blood/bone marrow disorders (myelodysplastic syndromes-MDS) in which the bone marrow does not produce enough healthy blood cells. People with MDS may have problems such as infections, anemia, and easy bleeding/bruising.

How do you give decitabine?

How should this medicine be used? Decitabine comes as a powder to be to be added to fluid and injected slowly over 3 hours intravenously (into a vein) by a doctor or nurse in a medical office or hospital outpatient clinic. It is usually injected every 8 hours for 3 days.

How is dacogen administered?

Dacogen is administered at a dose of 15 mg/m2 by continuous intravenous infusion over 3 hours repeated every 8 hours for 3 days. This cycle should be repeated every 6 weeks. Patients may be premedicated with standard anti-emetic therapy.

How effective is dacogen?

Overall, following an average of 3 courses of re-treatment with Dacogen™, overall anti-cancer responses were achieved in 45% of patients.

When do you hold decitabine?

In patients who have an active or uncontrolled infection, hold decitabine therapy until the infection resolves. Start growth factor and/or anti-infective therapy as clinically indicated. The use of decitabine in patients with hepatic disease has not been studied.

How effective is DACOGEN?

How long does it take decitabine to work?

How long does it take for patients to respond to treatment? In the clinical study, the median time for patients to achieve some level of remission for either CR or CRh was 2 months (with a range of 0.8 to 4.2 months).

Is DACOGEN the same as decitabine?

Dacogen is the trade name for decitabine. In some cases, health care professionals may use the trade name Dacogen when referring to the generic drug name decitabine.

Can decitabine be given subcutaneously?

Resource links provided by the National Library of Medicine Schedule A: decitabine will be administered subcutaneously (SQ) daily for 3 consecutive days (Days 1 to 3) every 28 days. The dose will be 20 mg/m^2/day.

How do you administer Dacogen 15 mg?

Administer Dacogen at a dose of 15 mg/m 2 by continuous intravenous infusion over 3 hours repeated every 8 hours for 3 days. Repeat cycles every 6 weeks upon hematologic recovery (ANC at least 1,000/µL and platelets at least 50,000/µL) for a minimum of 4 cycles. .

How often do you give Dacogen?

DACOGEN Regimen Options. Three Day Regimen. Administer DACOGEN at a dose of 15 mg/m 2 by continuous intravenous infusion over 3 hours repeated every 8 hours for 3 days. Repeat cycles every 6 weeks upon hematologic recovery (ANC at least 1,000/µL and platelets at least 50,000/µL) for a minimum of 4 cycles.

How is Dacogen administered in the treatment of leprosy?

Administer Dacogen at a dose of 15 mg/m 2 by continuous intravenous infusion over 3 hours repeated every 8 hours for 3 days. Repeat cycles every 6 weeks upon hematologic recovery (ANC at least 1,000/µL and platelets at least 50,000/µL) for a minimum of 4 cycles.

What is the schedule for HepB-CpG treatment?

Adhere to the 3-dose schedule minimum intervals of 4 weeks between dose 1 and 2, 8 weeks between dose 2 and 3, and 16 weeks between dose 1 and 3. However, if HepB-CpG is substituted for dose 2 of HepB-alum, a provider has the option of administering the next dose of HepB-CpG a minimum of 4 weeks from the previous dose for a complete series.